Chrome Version       : 73.0.3678.0 (official build) canary (64bit) (cohort: Clang-64)
OS Version: Windows 10.0

URLs (if applicable) : https://pbs.twimg.com/media/CqzwpPnWEAAiGjW.jpg

Other browsers tested:
     Safari: OK
    Firefox: OK (developer edition)
    IE/Edge: OK
     Chrome: OK (Stable)

What steps will reproduce the problem?
1. Access the above link on the latest Chrome Canary.
2. the page returns connection refused, but it works on other browsers.

What is the expected result?
The page loads and image is loaded properly.

What happens instead of that?
Connection refused


Please provide any additional information below. Attach a screenshot if
possible.

    I am not sure but I think websites with DigiCert-based certificates are dropped on the request.
    When I try accessing the website with a self-generated and self-trusted certificate, the connection works without a problem.
    I'm guessing whether this has been caused by https certificate checks or not.
    I'm not sure if this connection drop is related with the Symantec distrust events. 
    Because of this issue, many websites like GitHub and Twitter are not functioning properly.

User-Agent: Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/73.0.3678.0 Safari/537.36