When I open a PDF file in Chrome, it displays the PDF in a new tab for a few seconds, then the screen becomes grey (or white if setting "Use Hardware acceleration" is unchecked). 
Fun fact if I switch to another tab of my favorite browser and come back to the tab where the PDF was opened, it appears again and do not vanish any more. It's my current workaround, but not satisfying for my clients.

I've seen many post on the same subject, but all closed although I still have this issue.
What I've tried until then:
- clear cache and cookies
- uncheck "Use hardware acceleration when available"
- same using Incognito mode



Below device and OS details, attached the result of chrome://net-internals/ capture while downloading the PDF



About:version
Google Chrome	68.0.3440.84 (Official Build) (64-bit)
Revision	520a5c14b858e4b1441dd2d3bab9bc745911a23b-refs/branch-heads/3440@{#774}
OS	Mac OS X
JavaScript	V8 6.8.275.24
Flash	30.0.0.134 /Users/david/Library/Application Support/Google/Chrome/PepperFlash/30.0.0.134/PepperFlashPlayer.plugin
User Agent	Mozilla/5.0 (Macintosh; Intel Mac OS X 10_12_6) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.84 Safari/537.36
Command Line	/Applications/Google Chrome.app/Contents/MacOS/Google Chrome --flag-switches-begin --flag-switches-end
Executable Path	/Applications/Google Chrome.app/Contents/MacOS/Google Chrome
Profile Path	/Users/david/Library/Application Support/Google/Chrome/Default
Variations	c134752e-95b424ac
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Deleted: net-internals.html 94.6 KB

net-internals.html 94.6 KB View Download