the chrome 53 look good,It think this file cause problem:
 
chromium/src/ui/android/java/src/org/chromium/ui/base/EventForwarder.java

    public boolean onTouchEvent(MotionEvent event) {
        // TODO(mustaq): Should we include MotionEvent.TOOL_TYPE_STYLUS here?
        // crbug.com/592082
        if (event.getToolType(0) == MotionEvent.TOOL_TYPE_MOUSE) {
            // Skip firing mouse events in the follwoing cases:
            // - In Android L and below, where mouse button info is incomplete.
            // - A move w/o a button press, which represents a trackpad scroll. Real mouse moves w/o
            //   buttons goes to onHoverEvent.
            final int apiVersion = Build.VERSION.SDK_INT;
            final boolean isTouchpadScroll = event.getButtonState() == 0
                    && (event.getActionMasked() == MotionEvent.ACTION_DOWN
                               || event.getActionMasked() == MotionEvent.ACTION_MOVE
                               || event.getActionMasked() == MotionEvent.ACTION_UP);

            if (apiVersion >= android.os.Build.VERSION_CODES.M && !isTouchpadScroll) {
                return onMouseEvent(event);
            }
        }

        final boolean isTouchHandleEvent = false;
        return sendTouchEvent(event, isTouchHandleEvent);
    }


when on mouse drag or move,it also has the touch event, but this code filter the touch event and call onMouseEvent method.Then the webpage can't respond any operation.

when I remove it,it will cause an other problem and I have no idea how to fix

so,can any one confirmed it.

The code you pointed doesn't cause the problem. The issue here is chrome on Android doesn't support drag anything other than data transfer format "text". So it's not able to drag a normal image with mouse on Android.
If the image has `event.dataTransfer.setData("text", any_drag_data)`, you should be able to drag it.

I'll work on fixing this in probably next month, but not sure when :)

emm....I means the image can't scroll with mouse but can respond with the finger touch.

I see. Before Chrome 59, mouse input appeared as touch is because we had incomplete mouse handling code in Chrome.  For consistent with mouse behavior on other platform, mouse on Android is now behavior as mouse on desktop. You should be able to use mouse wheel to scroll a page.

yes,I use mouse whell to scroll a page normally.

But in this case,mouse wheel not invalid because it only use for scroll down and scroll up. That website is special,the image only scroll left or right,so the mouse wheel not work. 

I'd say the page is not designed to work with mouse. .. mustaq@, any thoughts about this usage?

I agree with eirage@: the page seemes not designed for mouse.

We had an incomplete event path for mouse in Android so those events used to appear as touch, and pages would only see broken mouse events.  It was fixed in Chrome 58: https://www.chromestatus.com/feature/5642080642662400

We recommend using PointerEvents for pages that need to support mouse and touch (and stylus) interactions.