Unable to reproduce the issue on Win-10 using chrome reported version #67.0.3396.2 and latest canary #68.0.3397.0.

Attached a screen cast for reference.

Following are the steps followed to reproduce the issue.
------------
1. Navigated to https://reddit.com/r/all/
2. Used middle click to open other links in new tab.
3. Repeated by clicking 5-6 links and scrolled on the main page.
4. Observed that scrolling worked correctly without any issues.

trinityxtmzz@ - Could you please check the issue on latest canary #68.0.3397.0 by creating a new profile without any apps and extensions and please let us know if the issue still persist or not.
Also please check the attached screen cast and please let us know if anything missed from our end.

Thanks...!!

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krajshree@ - Couldn't reproduce the problem on neither my nor a clean profile using Canary version 68.0.3397.0. Issue seems to have solved itself and was related to something on my end.

No idea what caused it as I made no changes to any settings nor software (apart from updates). Side note: the extensions I am using are uBlock Origin and Chrome Remote Desktop.

Thanks for your efforts!

Thank you for providing more feedback. Adding the requester to the cc list.

For more details visit https://www.chromium.org/issue-tracking/autotriage - Your friendly Sheriffbot

Unable to reproduce the issue on chrome reported version 67.0.3396.2 using Windows-10 with steps mentioned below:
1) Launched chrome reported version and installed uBlock Origin and Chrome Remote Desktop(as per comment#3)
2) Navigated to https://reddit.com/r/all/ and middle click on mouse to open other links in new tab
3. Repeated by clicking 5-6 links and scrolled on the main page, didn't observed any issues in scrolling the page.

@Reporter: Please find the attached screencast for your reference, as per comment#3 it seems issue is not reproducible from your end, could you please provide your confirmation on closing the issue.

Thanks!

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Running Canary version 68.0.3398.0.

Issue for me is reproducible using my profile and on the default Guest profile. It's also reproducible on YouTube and MyAnimeList, which makes me assume it's reproducible everywhere, but is easiest reproduced on reddit.

After some extended testing, I assume I found the cause of the issue.

Steps to reproduce the issue:
1. Go to reddit.com
2. Spam middle mouse button on a link to open it in new tabs
3. Try scrolling with mouse wheel
4. Redo steps 2-3 until scrolling stops working

Steps to fix the issue:
1. Hold middle mouse click to activate the middle mouse click scrolling feature and move your mouse in any direction to reset the mouse scroll wheel "lock" caused by the issue.

Issue seems to be caused by multiple consecutive middle mouse clicks on a link in quick succession. Basically triggering the middle mouse click scrolling feature while you are opening a link using middle mouse click, without changing your mouse cursor (it doesn't change the look of the cursor like when you hold down middle mouse button to scroll) which locks your mouse scroll wheel. Using the middle mouse click scrolling feature resets/removes the mouse wheel scroll "lock" caused by the issue.

I don't know if the explanation was clear enough, so I hope you understand what I mean.

Thank you for providing more feedback. Adding the requester to the cc list.

For more details visit https://www.chromium.org/issue-tracking/autotriage - Your friendly Sheriffbot

Unable to reproduce the issue on chrome reported version 67.0.3396.2 and on latest chrome 68.0.3398.0 using Windows-10 with steps as mentioned in comment#6, as the issue is not reproducible from TE end, hence removing Needs-Bisect label, Please find the attached screencast for reference.

Thanks!

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This is really infuriating. I also tried with a normal mouse, without any mouse software, and was able to reproduce the issue in canary but not on firefox nor edge.

I couldn't reproduce it on my old desktop either, leaving me with only the assumption that it could be somehow related to my touchpad's 2 finger pinch/zoom function.

Doesn't seem like anyone else is having the same issue. Since I already found a quick fix/workaround, I guess I can just learn to live with it. 

Ticket can be closed. Thanks for your time and efforts.

As per comment#9 from the reporter, closing the issue and marking it as Won't fix.

Thanks!