UserAgent: Mozilla/5.0 (X11; CrOS x86_64 10323.67.0) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/65.0.3325.209 Safari/537.36
Platform: 10323.67.0 (Official Build) stable-channel eve

Example URL:

Steps to reproduce the problem:
1. Connect Bluetooth mouse to Pixelbook
2. Connect Jaybird Run (both buds) to Pixelbook
3. Play audio

What is the expected behavior?
Audio plays with no issues

What went wrong?
Audio cuts in and out on Jaybird Run while the mouse is also connected. As soon as I disconnect the mouse, the buds work fine. 

I can keep the mouse connected and audio playing correctly only if one of the buds is connected. Connecting them both causes issues/interference.

Did this work before? N/A 

Is it a problem with Flash or HTML5? N/A

Does this work in other browsers? N/A

Chrome version: 65.0.3325.209  Channel: stable
OS Version: 10323.67.0
Flash Version: Shockwave Flash 29.0 r0

Contents of chrome://gpu: 

Jaybird Run are true wireless headphones. 
https://jaybirdsport.com/en-us/run-true-wireless-sport-headphones.html#985-000688
Right bud is the primary one that connects to the computer 
and it connects to left bud also via bluetooth. If I have both buds on and connected to the Pixelbook, and also bluetooth mouse connected, the audio cuts in and out and it is practically unusable.

Removing mouse from the equation removes the issue completely. I was also able to use the mouse when I only connect the primary bud (right one). This is also OK for me sometimes when I can listen to podcasts or radio in mono. This is not an issue on a Windows computer.