Unable to reproduce this issue on reported version 64.0.3282.186 with URLS http://www.pdf995.com/samples/pdf.pdf and https://news.google.com/news/ned=in&gl=IN&hl=en-IN . Printing 1st and 2nd page with 2 sided checked .. Observed pages printed without any issue. Used RICOH network printer for testing. It looks like issue is specific to printer. Hence adding TE-Hardwaredependency label.

@REporter: Is this issue reproducible on any particular URL? If so please provide sample URL where you are seeing this issue. This info would help in further triaging of the issue.

Thanks!

I will see if we can test it with one of those sitesyou used. The items being printed are usually google documents that the teacher has worked on so it would be hard to give you a URL to print.

I hesitate to say it is these printer models specifically because of it happening to two different printers and both are modles that we use extensively throughout our school district. Regardless, I will try to reproduce with fewer variables for you and comment again.

Thank you for providing more feedback. Adding the requester to the cc list.

For more details visit https://www.chromium.org/issue-tracking/autotriage - Your friendly Sheriffbot

Can you try a non-Lexmark printer with a duplexer, at home or at school, and see if this is problem Lexmark specific?

Can you also try skipping Print Preview and see if the system print dialog has the same problem with the Lexmark printers? e.g. Open Wikipedia, and press ctrl + shift + p to print.

The user's in question do not have access to a non-Lexmark printer. I have been able to reproduce with the print dialog and skipping the print preview, and have now tried a wikipedia article, and both of the URL's that were tested before.  

Thank you for providing more feedback. Adding the requester to the cc list.

For more details visit https://www.chromium.org/issue-tracking/autotriage - Your friendly Sheriffbot

Assuming the user in question is someone else - I understand if the user does not have a non-Lexmark printer. How about you? Do you have a non-Lexmark, duplex-capable printer to test with?

We'll assume the issue is Lexmark-specific for now.

I don't have the printers, but I did download the driver from Lexmark's website. http://support.lexmark.com/index?locale=EN&page=product&userlocale=EN_US&productCode=LEXMARK_MS312#2

The recommended 64-bit drivers for Windows 10 is 
"Lexmark MS310-MS410 Series Driver and Software" version 2.7.1.0 from 02/26/2017.

Installing the driver on the FILE port to save the print output to file, I tried printing from Notepad twice in simplex and duplex mode. The output files were the same size, but some bytes were 0x34 and 0x35 in the two modes, respectively. Presumably those are the control codes to tell the printer what to do.

Then I tried printing from Chrome using Print Preview, and I got similar results. So by looking at the Lexmark driver behavior, the duplex checkbox in Print Preview is certainly doing something. And that something is similar to what happens in Notepad.