Chrome Version: 61.0.3122.0 (Official Build) canary(64-bit)
OS: Windows 10 Version 1703 (OS Build 16199.1000) 64-bit

What steps will reproduce the problem?
(1) Start the NVDA screen reader and Chrome.
(2) Press control+shift+n to open a new Incognito window.
(3) Open this URL: https://gitter.im/nvaccess/nvda
(4) Wait a few seconds for the page to load.
(5) Press NVDA+f5 to refresh the content.
(6) Press control+end to go to the bottom of the document.

What is the expected result?
The bottom line should be "SIGN IN TO START TALKING".

What happens instead?
The bottom line is "Browser, Desktop and Mobile Apps."

If this works as expected the first time, try closing the window and repeating.

Additional info:
This is a little intermittent, though I can reproduce it every time with the above steps. Timing seems to play a significant part, unfortunately; if you simply refresh the page, sometimes it doesn't happen, as it loads faster. The NVDA+f5 bit isn't always necessary, but sometimes, we can get to the iframe initially and then it breaks later.

When this occurs, the accessible for the content iframe (tag: iframe; id: content-frame) returns E_FAIL when we call IAccessibleHypertext::hyperlink(0). nHyperlinks does return 1. You can get to the document using accNavigate, just not with hyperlink(0) (which is the normal way to access this because there is an embedded object character exposed by the text interface).

Impact: This makes Gitter unusable for Chrome + NVDA users most of the time.