Tried with other postscript drivers such as Xerox, Generic, etc. The problem seems to have a common denominator with the pdf preview in Chrome, regardless of print driver brand or type.

Also the problem is in Chrome 53 and even Chrome 41.

Looping to folks in the print team for a repro.

This is a known issue. We are working on adding a path to output postscript when printing to postscript printers, which will reduce the spool size. This fix will hopefully be available in Canary behind a flag in the next week or so. 

We added an experimental postscript printing path that is currently behind a flag in the latest Canary (58.0.3000.0). Please try this out and provide feedback on whether this helps with the spool size. You will need to:
1. Open Canary (58.0.3000.0+)
2. Navigate to chrome://flags and scroll down/search for PostScript Printing
3. Select "Enabled" from the dropdown (Default is currently Disabled).
4. Relaunch Canary so that the change takes effect.

Ok thanks. Once this is in the official Chrome browser will this be integrated or controllable by GPO? I can't deploy this to all users.

We currently plan to make this the default in Stable if everything goes well during the roll-out process.

Update: Landed a new patch to improve postscript language level detection capabilities: https://codereview.chromium.org/2691653002/ 

This should further reduce spool sizes on many documents for many level 3 capable postscript printers. Canary should update in the next few days to include this patch.

If there is a specific PDF file you would like us to test with, please attach it here, so we can make sure our printing improvements help with your print job size.

And if you can mention the specific PS driver version you have installed, that's helpful too.

Is this still an issue in Chrome 63 or newer? We finalized the post script printing change a while ago.

Closing this out as PostScript printing was finalized a long time ago and we haven't heard back for a year.