Able to repro without animations:
<style>
* { transform: scale(401097138271278291218014369784239731996273651907446632432050481860968837260646849527963905321140416504885948851035728884554668596377381844301691779646212276883999347210107904321400853234770400262630966685414177300637226084969485531323928171747339097329680466618459981653096907825383901203435465119229388903918693402127369724991051786999555709460879796564837102452367628787119790434501380107047836355838879441103978499945667529484302237233525892600799265138305038712034566566617672453247882237070896, 5); }
</style>

Using Code Search for the file, "MathExtras.h", assigning to the concern owner.
Suspecting Commit#
https://chromium.googlesource.com/chromium/src/+/b37bdbd63ea254bbaaab5e1094cbe37c441f4bb2

@ricea -- Could you please look into the issue, kindly re-assign if this is not related to your changes.
Thank You.

Need a proper debug build to get line information, but based on a stack trace from a release build and a bit of code search and imagination, the problem appears to be this line in third_party/WebKit/Source/core/layout/LayoutGeometryMap.cpp:

    ASSERT(enclosingIntRect(layoutObjectMappedResult) ==
               enclosingIntRect(result.boundingBox()) ||
           layoutObjectMappedResult.mayNotHaveExactIntRectRepresentation() ||
           result.boundingBox().mayNotHaveExactIntRectRepresentation());

As such, assigning chrishtr@ who last tried to fix this assert.

Detailed report: https://clusterfuzz.com/testcase?key=6464587770888192

Job Type: linux_debug_content_shell_drt
Crash Type: CHECK failure
Crash Address: 
Crash State:
  !std::isnan(static_cast<double>(value)) in MathExtras.h
  int clampTo<int, float>
  blink::FlooredIntPoint
  
Sanitizer: address (ASAN)

Reproducer Testcase: https://clusterfuzz.com/download?testcase_id=6464587770888192


See https://github.com/google/clusterfuzz-tools for more information.

This issue has been Available for over a year. If it's no longer important or seems unlikely to be fixed, please consider closing it out. If it is important, please re-triage the issue.

Sorry for the inconvenience if the bug really should have been left as Available.

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