Issue 25959 landed a fork to Chromium's SQLite to propagate time-machine exclusions from database files to journals. Using a SQLite VFS could move this code into sql/ and remove the custom code from SQLite.
Additionally, issue 537742 has resulted in a long tail of crashes, mostly invalid "disk lost" cases on Windows (see comment 98 and others). If Chromium had a custom VFS, then the xFetch implementation could use a structured exception handler to catch those crashes (maybe).
[Yes, I admit those two bugs are completely unrelated except by implementation strategy. And yet it doesn't seem big enough to warrant a blocking bug and two blocked bugs.]
Comment 1 by bugdroid1@chromium.org
, Jan 24 2017