Very frequently happens.
OS: Windows 10

$ ninja content_shell
[1/137] CXX obj/third_party/WebKit/Source/core/remaining/LocalFrame.obj
FAILED: obj/third_party/WebKit/Source/core/remaining/LocalFrame.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/remaining/LocalFrame.obj.rsp /c ../../third_party/WebKit/Source/core/frame/LocalFrame.cpp /Foobj/third_party/WebKit/Source/core/remaining/LocalFrame.obj /Fd"obj/third_party/WebKit/Source/core/remaining_cc.pdb"
c:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\vc\include\type_traits(260): fatal error C1060: compiler is out of heap space
[2/137] CXX obj/third_party/WebKit/Source/core/remaining/Editor.obj
FAILED: obj/third_party/WebKit/Source/core/remaining/Editor.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/remaining/Editor.obj.rsp /c ../../third_party/WebKit/Source/core/editing/Editor.cpp /Foobj/third_party/WebKit/Source/core/remaining/Editor.obj /Fd"obj/third_party/WebKit/Source/core/remaining_cc.pdb"
c:\build\src\chrome1\src\third_party\webkit\source\wtf\hashmap.h(239): fatal error C1060: compiler is out of heap space
[3/137] CXX obj/third_party/WebKit/Source/core/remaining/LocalDOMWindow.obj
FAILED: obj/third_party/WebKit/Source/core/remaining/LocalDOMWindow.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/remaining/LocalDOMWindow.obj.rsp /c ../../third_party/WebKit/Source/core/frame/LocalDOMWindow.cpp /Foobj/third_party/WebKit/Source/core/remaining/LocalDOMWindow.obj /Fd"obj/third_party/WebKit/Source/core/remaining_cc.pdb"
c:\build\src\chrome1\src\third_party\webkit\source\platform\transforms\transformoperation.h(83): fatal error C1060: compiler is out of heap space
[4/137] CXX obj/third_party/WebKit/Sou...re/remaining/InputMethodController.obj
FAILED: obj/third_party/WebKit/Source/core/remaining/InputMethodController.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/remaining/InputMethodController.obj.rsp /c ../../third_party/WebKit/Source/core/editing/InputMethodController.cpp /Foobj/third_party/WebKit/Source/core/remaining/InputMethodController.obj /Fd"obj/third_party/WebKit/Source/core/remaining_cc.pdb"
c:\build\src\chrome1\src\third_party\webkit\source\wtf\typetraits.h(170): fatal error C1060: compiler is out of heap space
[5/137] CXX obj/third_party/WebKit/Source/core/remaining/DataTransfer.obj
FAILED: obj/third_party/WebKit/Source/core/remaining/DataTransfer.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/remaining/DataTransfer.obj.rsp /c ../../third_party/WebKit/Source/core/clipboard/DataTransfer.cpp /Foobj/third_party/WebKit/Source/core/remaining/DataTransfer.obj /Fd"obj/third_party/WebKit/Source/core/remaining_cc.pdb"
c:\build\src\chrome1\src\third_party\webkit\source\wtf\vector.h(305): fatal error C1060: compiler is out of heap space
[6/137] CXX obj/third_party/WebKit/Source/core/remaining/LayoutBlockFlow.obj
FAILED: obj/third_party/WebKit/Source/core/remaining/LayoutBlockFlow.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/remaining/LayoutBlockFlow.obj.rsp /c ../../third_party/WebKit/Source/core/layout/LayoutBlockFlow.cpp /Foobj/third_party/WebKit/Source/core/remaining/LayoutBlockFlow.obj /Fd"obj/third_party/WebKit/Source/core/remaining_cc.pdb"
c:\build\src\chrome1\src\third_party\webkit\source\core\editing\editingstyle.h(203): fatal error C1060: compiler is out of heap space
[7/137] CXX obj/third_party/WebKit/Source/core/remaining/SelectorChecker.obj
FAILED: obj/third_party/WebKit/Source/core/remaining/SelectorChecker.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/remaining/SelectorChecker.obj.rsp /c ../../third_party/WebKit/Source/core/css/SelectorChecker.cpp /Foobj/third_party/WebKit/Source/core/remaining/SelectorChecker.obj /Fd"obj/third_party/WebKit/Source/core/remaining_cc.pdb"
c:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\vc\include\type_traits(109): fatal error C1060: compiler is out of heap space
[8/137] CXX obj/third_party/WebKit/Source/core/remaining/TypingCommand.obj
FAILED: obj/third_party/WebKit/Source/core/remaining/TypingCommand.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/remaining/TypingCommand.obj.rsp /c ../../third_party/WebKit/Source/core/editing/commands/TypingCommand.cpp /Foobj/third_party/WebKit/Source/core/remaining/TypingCommand.obj /Fd"obj/third_party/WebKit/Source/core/remaining_cc.pdb"
c:\build\src\chrome1\src\third_party\webkit\source\core\editing\commands\typingcommand.cpp(712): fatal error C1060: compiler is out of heap space
[9/137] CXX obj/third_party/WebKit/Sou...e/core/remaining/MarkupAccumulator.obj
FAILED: obj/third_party/WebKit/Source/core/remaining/MarkupAccumulator.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/remaining/MarkupAccumulator.obj.rsp /c ../../third_party/WebKit/Source/core/editing/serializers/MarkupAccumulator.cpp /Foobj/third_party/WebKit/Source/core/remaining/MarkupAccumulator.obj /Fd"obj/third_party/WebKit/Source/core/remaining_cc.pdb"
c:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\vc\include\xlocnum(1046): fatal error C1060: compiler is out of heap space
[15/137] CXX obj/third_party/WebKit/Source/core/html/HTMLTextAreaElement.obj
FAILED: obj/third_party/WebKit/Source/core/html/HTMLTextAreaElement.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/html/HTMLTextAreaElement.obj.rsp /c ../../third_party/WebKit/Source/core/html/HTMLTextAreaElement.cpp /Foobj/third_party/WebKit/Source/core/html/HTMLTextAreaElement.obj /Fd"obj/third_party/WebKit/Source/core/html_cc.pdb"
c:\build\src\chrome1\src\third_party\webkit\source\platform\heap\heapallocator.h(137) : fatal error C1002: compiler is out of heap space in pass 2
[16/137] CXX obj/third_party/WebKit/So...e/core/remaining/EditorKeyBindings.obj
FAILED: obj/third_party/WebKit/Source/core/remaining/EditorKeyBindings.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/remaining/EditorKeyBindings.obj.rsp /c ../../third_party/WebKit/Source/core/editing/EditorKeyBindings.cpp /Foobj/third_party/WebKit/Source/core/remaining/EditorKeyBindings.obj /Fd"obj/third_party/WebKit/Source/core/remaining_cc.pdb"
c:\build\src\chrome1\src\third_party\webkit\source\core\editing\editorkeybindings.cpp(79): fatal error C1090: PDB API call failed, error code '24': '
[17/137] CXX obj/third_party/WebKit/Source/core/remaining/DragController.obj
FAILED: obj/third_party/WebKit/Source/core/remaining/DragController.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/remaining/DragController.obj.rsp /c ../../third_party/WebKit/Source/core/page/DragController.cpp /Foobj/third_party/WebKit/Source/core/remaining/DragController.obj /Fd"obj/third_party/WebKit/Source/core/remaining_cc.pdb"
c:\build\src\chrome1\src\third_party\webkit\source\wtf\hashtraits.h(274): fatal error C1060: compiler is out of heap space
[18/137] CXX obj/third_party/WebKit/So...ore/remaining/CompositeEditCommand.obj
FAILED: obj/third_party/WebKit/Source/core/remaining/CompositeEditCommand.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/remaining/CompositeEditCommand.obj.rsp /c ../../third_party/WebKit/Source/core/editing/commands/CompositeEditCommand.cpp /Foobj/third_party/WebKit/Source/core/remaining/CompositeEditCommand.obj /Fd"obj/third_party/WebKit/Source/core/remaining_cc.pdb"
c:\build\src\chrome1\src\third_party\webkit\source\wtf\hashtable.h(807): fatal error C1060: compiler is out of heap space
[19/137] CXX obj/third_party/WebKit/Source/core/dom/Document.obj
FAILED: obj/third_party/WebKit/Source/core/dom/Document.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/dom/Document.obj.rsp /c ../../third_party/WebKit/Source/core/dom/Document.cpp /Foobj/third_party/WebKit/Source/core/dom/Document.obj /Fd"obj/third_party/WebKit/Source/core/dom_cc.pdb"
c:\build\src\chrome1\src\third_party\webkit\source\wtf\typetraits.h(151): fatal error C1060: compiler is out of heap space
[45/137] CXX obj/third_party/WebKit/Source/core/html/HTMLInputElement.obj
FAILED: obj/third_party/WebKit/Source/core/html/HTMLInputElement.obj
ninja -t msvc -e environment.x64 -- "C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64/cl.exe" /nologo /showIncludes /FC @obj/third_party/WebKit/Source/core/html/HTMLInputElement.obj.rsp /c ../../third_party/WebKit/Source/core/html/HTMLInputElement.cpp /Foobj/third_party/WebKit/Source/core/html/HTMLInputElement.obj /Fd"obj/third_party/WebKit/Source/core/html_cc.pdb"
c:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\vc\include\xutility(917): fatal error C1060: compiler is out of heap space
Internal Compiler Error in C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64\cl.exe.  You will be prompted to send an error report to Microsoft later.
INTERNAL COMPILER ERROR in 'C:\build\depot_tools\win_toolchain\vs_files\95ddda401ec5678f15eeed01d2bee08fcbc5ee97\VC\bin\amd64\cl.exe'
    Please choose the Technical Support command on the Visual C++
    Help menu, or open the Technical Support help file for more information
[50/137] CXX obj/third_party/WebKit/Source/core/remaining/FrameView.obj
ninja: build stopped: subcommand failed.
exit status 1