The issue seems to be that the Android Cast SDK receives the URL with an unescaped parameter that is not recognized by the server when fetched by the Cast device:

- escaped, working URL:

http://content.uplynk.com
/channel/ext/1efe3bfc4d1e4b5db5e5085a535b510b/KTRKwatch.m3u8
?tc=1
&exp=1461257066933
&rn=9209.113141206697
&ct=c
&oid=1efe3bfc4d1e4b5db5e5085a535b510b
&eid=KTRKwatch
&ad=watchktrklive
&ad.adUnit=midroll
&ad.flex=0
&ad._v=2
&ad.kv=station%2Cktrk%2C_fw_vcid2%2Cd015_6276049784806122024%2Cdatg_yx_bk%2CtLmMj8hi999l252j
&sig=601e28d47fef565459fb40b90dae5c0c08224058c2c8b3f6cb5cd1402f4032f6

- sent by Clank, not working URL

http://content.uplynk.com
/channel/ext/1efe3bfc4d1e4b5db5e5085a535b510b/KTRKwatch.m3u8
?tc=1
&exp=1461256703583
&rn=1692.467108431245
&ct=c
&oid=1efe3bfc4d1e4b5db5e5085a535b510b
&eid=KTRKwatch
&ad=watchktrklive
&ad.adUnit=midroll
&ad.flex=0
&ad._v=2
&ad.kv=station,ktrk,datg_yx_bk,tLmMj8hi999l252j
&sig=f47ba01765109a16d3f97db626531d7274c5e9f68cf694c6d79eb0f6cf4aea5b

Note the difference between the penultimate parameters.

I also found the following issues and changes relevant:

https://bugs.chromium.org/p/chromium/issues/detail?id=366590
https://bugs.chromium.org/p/chromium/issues/detail?id=358157

https://chrome-internal-review.googlesource.com/#/c/161655/
https://chrome-internal-review.googlesource.com/#/c/159375/
https://chrome-internal-review.googlesource.com/#/c/158285/

The following revision refers to this bug:
  https://chromium.googlesource.com/chromium/src.git/+/e358d10bb42b0699c2db6276b57d6b9963be4b24

commit e358d10bb42b0699c2db6276b57d6b9963be4b24
Author: avayvod <avayvod@chromium.org>
Date: Tue Apr 26 09:48:23 2016

[Android,MediaFling] Fix the encoding issue with already encoded URLs for abc13.com/live

Also some cleanup of error handling, url type conversions and media type detection,
extend the UMA to cover more failure cases.

BUG= 605544 
TEST=unit tests + avayvod.github.io/mediaflingtest.html

Review URL: https://codereview.chromium.org/1907413002

Cr-Commit-Position: refs/heads/master@{#389735}

[modify] https://crrev.com/e358d10bb42b0699c2db6276b57d6b9963be4b24/chrome/android/java/src/org/chromium/chrome/browser/media/remote/DefaultMediaRouteController.java
[modify] https://crrev.com/e358d10bb42b0699c2db6276b57d6b9963be4b24/chrome/android/java/src/org/chromium/chrome/browser/media/remote/MediaUrlResolver.java
[modify] https://crrev.com/e358d10bb42b0699c2db6276b57d6b9963be4b24/chrome/android/junit/src/org/chromium/chrome/browser/media/remote/MediaUrlResolverTest.java
[modify] https://crrev.com/e358d10bb42b0699c2db6276b57d6b9963be4b24/chrome/browser/media/android/remote/remote_media_player_bridge.cc
[modify] https://crrev.com/e358d10bb42b0699c2db6276b57d6b9963be4b24/tools/metrics/histograms/histograms.xml

Ramine, could you please verify the fix?

Your change meets the bar and is auto-approved for M51 (branch: 2704)

Tested on '52.0.2718.2' Dev
On LG G3/LRX21T -> Pass
Nexus 5X/NRD26  -> Pass

Othere sites tested:
m.youtube.com
dailymotion
bbc.com

Other cast enabled video's tested with 52.0.2718.2' & '50.0.2661.94'
LG G3/LRX21T
Samsung Galaxy S7/MMB29M
Nexus 5X/NRD28

www.cnn.com
m.youtube.com
http://videojs.com/
http://html5-demos.appspot.com/static/fullscreen.html
https://developer.apple.com/streaming/examples/basic-stream.html
http://www.metacafe.com/
http://people.mozilla.org/~rgiles/2013/demo.html
https://www.facebook.com/
http://www.nytimes.com/
www.cnet.com

This issue has been approved for a merge. Please merge the fix to any appropriate branches as soon as possible!

If all merges have been completed, please remove any remaining Merge-Approved labels from this issue.

Thanks for your time! To disable nags, add the Disable-Nags label.

For more details visit https://www.chromium.org/issue-tracking/autotriage - Your friendly Sheriffbot

The following revision refers to this bug:
  https://chromium.googlesource.com/chromium/src.git/+/a8de7f8d6820d42bf0a476fd3029dd0cf0ae9c36

commit a8de7f8d6820d42bf0a476fd3029dd0cf0ae9c36
Author: Anton Vayvod <avayvod@google.com>
Date: Tue May 03 10:07:23 2016

[Android,MediaFling] Fix the encoding issue with already encoded URLs for abc13.com/live

Also some cleanup of error handling, url type conversions and media type detection,
extend the UMA to cover more failure cases.

BUG= 605544 
TEST=unit tests + avayvod.github.io/mediaflingtest.html

Review URL: https://codereview.chromium.org/1907413002

Cr-Commit-Position: refs/heads/master@{#389735}
(cherry picked from commit e358d10bb42b0699c2db6276b57d6b9963be4b24)

Review URL: https://codereview.chromium.org/1940273002 .

Cr-Commit-Position: refs/branch-heads/2704@{#350}
Cr-Branched-From: 6e53600def8f60d8c632fadc70d7c1939ccea347-refs/heads/master@{#386251}

[modify] https://crrev.com/a8de7f8d6820d42bf0a476fd3029dd0cf0ae9c36/chrome/android/java/src/org/chromium/chrome/browser/media/remote/DefaultMediaRouteController.java
[modify] https://crrev.com/a8de7f8d6820d42bf0a476fd3029dd0cf0ae9c36/chrome/android/java/src/org/chromium/chrome/browser/media/remote/MediaUrlResolver.java
[modify] https://crrev.com/a8de7f8d6820d42bf0a476fd3029dd0cf0ae9c36/chrome/android/junit/src/org/chromium/chrome/browser/media/remote/MediaUrlResolverTest.java
[modify] https://crrev.com/a8de7f8d6820d42bf0a476fd3029dd0cf0ae9c36/chrome/browser/media/android/remote/remote_media_player_bridge.cc
[modify] https://crrev.com/a8de7f8d6820d42bf0a476fd3029dd0cf0ae9c36/tools/metrics/histograms/histograms.xml

Verified with Chrome Beta '51.0.2704.36' (Samsung Galaxy S7/MMB29M)